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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NF2
All Species:
8.79
Human Site:
S587
Identified Species:
17.58
UniProt:
P35240
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.73
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35240
NP_000259.1
595
69690
S587
L
T
L
Q
S
A
K
S
R
V
A
F
F
E
E
Chimpanzee
Pan troglodytes
XP_001136298
595
69538
S587
L
T
L
Q
S
A
K
S
R
V
A
F
F
E
E
Rhesus Macaque
Macaca mulatta
XP_001106489
595
69702
S587
L
T
L
Q
S
T
K
S
R
V
A
F
F
E
E
Dog
Lupus familis
XP_534729
596
69793
K587
K
L
T
L
Q
S
A
K
S
R
V
A
F
F
E
Cat
Felis silvestris
Mouse
Mus musculus
P46662
596
69758
K587
K
L
T
L
Q
S
A
K
S
R
V
A
F
F
E
Rat
Rattus norvegicus
Q63648
586
68693
K569
S
D
S
G
T
S
S
K
H
N
T
I
K
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521866
636
73533
Q577
G
G
P
K
K
H
H
Q
G
T
R
S
P
V
S
Chicken
Gallus gallus
Q9PU45
583
68536
R576
R
Q
G
N
T
K
Q
R
I
D
E
F
E
A
M
Frog
Xenopus laevis
NP_001086957
585
68810
K577
G
S
K
Q
N
T
I
K
K
A
R
R
A
V
C
Zebra Danio
Brachydanio rerio
NP_001122179
593
69546
R586
T
L
Q
S
T
K
S
R
V
A
F
F
Q
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24564
635
74474
R628
K
S
G
S
T
K
A
R
V
A
F
F
E
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781142
608
70697
R601
T
Q
G
S
T
R
A
R
V
A
F
F
E
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.4
99.8
99.5
N.A.
98.3
95.1
N.A.
61.7
44.8
86.8
82.5
N.A.
47.4
N.A.
N.A.
56.5
Protein Similarity:
100
97.6
99.8
99.5
N.A.
99.3
96.6
N.A.
76.5
65.5
92.7
91.2
N.A.
66.3
N.A.
N.A.
75.4
P-Site Identity:
100
100
93.3
13.3
N.A.
13.3
0
N.A.
0
6.6
6.6
13.3
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
20
N.A.
20
20
N.A.
6.6
20
26.6
20
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
34
0
0
34
25
17
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
0
25
50
42
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
25
59
42
17
0
% F
% Gly:
17
9
25
9
0
0
0
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
9
9
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
9
0
0
9
0
0
0
% I
% Lys:
25
0
9
9
9
25
25
34
9
0
0
0
9
9
0
% K
% Leu:
25
25
25
17
0
0
0
0
0
0
0
0
0
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
9
9
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
9
% P
% Gln:
0
17
9
34
17
0
9
9
0
0
0
0
9
0
0
% Q
% Arg:
9
0
0
0
0
9
0
34
25
17
17
9
0
0
0
% R
% Ser:
9
17
9
25
25
25
17
25
17
0
0
9
0
0
9
% S
% Thr:
17
25
17
0
42
17
0
0
0
9
9
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
25
25
17
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _